Mild ketone formation via Ni-catalyzed reductive coupling of unactivated alkyl halides with acid anhydrides.
نویسندگان
چکیده
Ni-catalyzed ketone formation through mild reductive coupling of a diverse set of unactivated alkyl bromides and iodides with particularly aryl acid anhydrides was successfully developed using zinc as the terminal reductant. These conditions also allow direct coupling of alkyl iodides with aryl acids in the presence of Boc(2)O and MgCl(2).
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 56 شماره
صفحات -
تاریخ انتشار 2012